Pub. Date : 1992 Jul-Aug
PMID : 1427443
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Ultrastructural, immunologic and clinical follow-up of five patients with HCL treated with interferon (IFN) for more than three years. | Hydrochloric Acid | interferon alpha 1 | Homo sapiens |
| 2 | BACKGROUND: Treatment results in HCl have been improved by the use of alpha-IFN, which is now the standard first-line therapy for this disease, but the mechanism of IFN action is still unclear. | Hydrochloric Acid | interferon alpha 1 | Homo sapiens |
| 3 | BACKGROUND: Treatment results in HCl have been improved by the use of alpha-IFN, which is now the standard first-line therapy for this disease, but the mechanism of IFN action is still unclear. | Hydrochloric Acid | interferon alpha 1 | Homo sapiens |
| 4 | METHODS: We assessed the phenotype membrane and ultrastructural changes induced in HCs by long-term alpha-IFN treatment in five pts with HCL; membrane-bound Il 2-R on PHA-stimulated PBL, the release of IL 2-R by PHA-stimulated PBL and the serum levels of s-IL 2-R were also determined in one pt. | Hydrochloric Acid | interferon alpha 1 | Homo sapiens |
| 5 | RESULTS: The surface immunological phenotype, mainly the HCL-related surface antigen CD25, changed after IFN treatment, dropping from abnormally high to normal values. | Hydrochloric Acid | interferon alpha 1 | Homo sapiens |