Pub. Date : 1992 Nov 1
PMID : 1417000
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Modulation of CYP3A1 and CYP3A2 mRNA expression by dexamethasone and by phenobarbital has been studied in immature (21-day-old) and adult (90-day-old) rat liver. | Dexamethasone | cytochrome P450, family 3, subfamily a, polypeptide 2 | Rattus norvegicus |
| 2 | Modulation of CYP3A1 and CYP3A2 mRNA expression by dexamethasone and by phenobarbital has been studied in immature (21-day-old) and adult (90-day-old) rat liver. | Phenobarbital | cytochrome P450, family 3, subfamily a, polypeptide 2 | Rattus norvegicus |
| 3 | However, CYP3A2 mRNA, although physiologically extinguished in the adult females, still responds to dexamethasone stimulation. | Dexamethasone | cytochrome P450, family 3, subfamily a, polypeptide 2 | Rattus norvegicus |