Title : Human interleukin-1 receptor antagonist. High yield expression in E. coli and examination of cysteine residues.

Pub. Date : 1992 Sep 21

PMID : 1388125






2 Functional Relationships(s)
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Protein Name
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1 This recombinant IL-1ra molecule possessed full binding activity to the IL-1 receptor (type I) and totally inhibited IL-1-induced PGE2 production by human dermal fibroblasts. Dinoprostone interleukin 1 receptor antagonist Homo sapiens
2 Radioalkylation and analysis of V8-derived IL-1ra peptides indicate that the four cysteines present in the IL-1ra are not disulphide-linked. Cysteine interleukin 1 receptor antagonist Homo sapiens