Pub. Date : 1992 Sep
PMID : 1387412
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Human dermal fibroblast interleukin-1 receptor antagonist (IL-1ra) and interleukin-1 beta (IL-1 beta) mRNA and protein are co-stimulated by phorbol ester: implication for a homeostatic mechanism. | Phorbol Esters | interleukin 1 receptor antagonist | Homo sapiens |
| 2 | Human dermal fibroblast interleukin-1 receptor antagonist (IL-1ra) and interleukin-1 beta (IL-1 beta) mRNA and protein are co-stimulated by phorbol ester: implication for a homeostatic mechanism. | Phorbol Esters | interleukin 1 receptor antagonist | Homo sapiens |
| 3 | Polymerase chain reaction amplification of reverse-transcribed mRNA with primers specific for the intracellular form of interleukin-1 receptor antagonist detected cDNA fragments present in both unstimulated and phorbol ester-stimulated fibroblasts, identical in molecular size to that in unstimulated keratinocytes. | Phorbol Esters | interleukin 1 receptor antagonist | Homo sapiens |
| 4 | Amplification with primers specific for the secretory form of interleukin-1 receptor antagonist, however, detected cDNA fragments in phorbol ester-stimulated fibroblasts and phytohemagglutinin-stimulated peripheral mononuclear cells, but not in unstimulated fibroblasts or keratinocytes. | Phorbol Esters | interleukin 1 receptor antagonist | Homo sapiens |
| 5 | By ethidium bromide visualization of amplified cDNA derived from serially diluted total cellular RNA and by Southern blot hybridization analysis of amplified cDNA, we have demonstrated that fibroblast interleukin-1 receptor antagonist mRNA and interleukin-1 beta mRNA were co-stimulated by phorbol ester. | Ethidium | interleukin 1 receptor antagonist | Homo sapiens |
| 6 | By ethidium bromide visualization of amplified cDNA derived from serially diluted total cellular RNA and by Southern blot hybridization analysis of amplified cDNA, we have demonstrated that fibroblast interleukin-1 receptor antagonist mRNA and interleukin-1 beta mRNA were co-stimulated by phorbol ester. | Phorbol Esters | interleukin 1 receptor antagonist | Homo sapiens |
| 7 | Similarly, ELISA demonstrated that fibroblast cytoplasmic interleukin-1 receptor antagonist protein and interleukin-1 beta protein were co-stimulated by phorbol ester. | Phorbol Esters | interleukin 1 receptor antagonist | Homo sapiens |