Pub. Date : 1992 Mar
PMID : 1371775
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In our pursuit of cytokines affecting basophil function, we studied the effect of MCAF on histamine secretion from basophils. | Histamine | C-C motif chemokine ligand 2 | Homo sapiens |
| 2 | MCAF caused dose-dependent release of histamine at concentrations of 10(-8) and 10(-7) M, and the mean release was 31.25 +/- 2.9% at the highest concentration. | Histamine | C-C motif chemokine ligand 2 | Homo sapiens |
| 3 | All 20 subjects responded to MCAF with significant histamine release. | Histamine | C-C motif chemokine ligand 2 | Homo sapiens |
| 4 | The histamine release was significantly correlated between MCAF and HRF (P less than 0.01), but not between MCAF and anti-IgE (P greater than 0.05). | Histamine | C-C motif chemokine ligand 2 | Homo sapiens |
| 5 | The histamine release by MCAF was complete within the first 3 min. | Histamine | C-C motif chemokine ligand 2 | Homo sapiens |
| 6 | MCAF-induced degranulation was a calcium-dependent process. | Calcium | C-C motif chemokine ligand 2 | Homo sapiens |