Title : Inhibition of leukotriene B4(LTB4) by recombinant interleukin-1 receptor antagonist (IL-1RA) on human monocytes.

Pub. Date : 1992

PMID : 1332453






6 Functional Relationships(s)
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1 In accordance with these data our results show that the pretreatment, for 60 min, of purified human peripheral monocytes with IL-1ra at different concentrations (0.25-250 ng/ml) inhibits, in a dose-dependent manner, the generation of LTB4 released after 10 min treatment with calcium ionophore A23187 (5 microM). Calcimycin interleukin 1 receptor antagonist Homo sapiens
2 Inhibition of leukotriene B4(LTB4) by recombinant interleukin-1 receptor antagonist (IL-1RA) on human monocytes. Leukotriene B4 interleukin 1 receptor antagonist Homo sapiens
3 Inhibition of leukotriene B4(LTB4) by recombinant interleukin-1 receptor antagonist (IL-1RA) on human monocytes. Leukotriene B4 interleukin 1 receptor antagonist Homo sapiens
4 Recently, interleukin-1 receptor antagonist (IL-1ra), a natural inhibitor of IL-1 released by macrophages, has been reported to inhibit PGE2. Dinoprostone interleukin 1 receptor antagonist Homo sapiens
5 Recently, interleukin-1 receptor antagonist (IL-1ra), a natural inhibitor of IL-1 released by macrophages, has been reported to inhibit PGE2. Dinoprostone interleukin 1 receptor antagonist Homo sapiens
6 In accordance with these data our results show that the pretreatment, for 60 min, of purified human peripheral monocytes with IL-1ra at different concentrations (0.25-250 ng/ml) inhibits, in a dose-dependent manner, the generation of LTB4 released after 10 min treatment with calcium ionophore A23187 (5 microM). Calcium interleukin 1 receptor antagonist Homo sapiens