Title : Transcriptional regulation of cytokine expression by diethyldithiocarbamate in human HL-60 promyelocytic leukemia cells.

Pub. Date : 1992 Jul 22

PMID : 1322666






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 DDTC treatment also increased interleukin-alpha (IL-1 alpha), IL-1 beta, and tumor necrosis factor (TNF) expression in these cells. Ditiocarb tumor necrosis factor Homo sapiens
2 DDTC treatment also increased interleukin-alpha (IL-1 alpha), IL-1 beta, and tumor necrosis factor (TNF) expression in these cells. Ditiocarb tumor necrosis factor Homo sapiens
3 Transcriptional run-on analysis demonstrated that exposure to DDTC increased the rate of TNF gene transcription in HL-60 cells. Ditiocarb tumor necrosis factor Homo sapiens
4 These data suggest that the myeloprotective effects of DDTC may be mediated, at least in part, by the induction of TNF, IL-1 alpha, and IL-1 beta. Ditiocarb tumor necrosis factor Homo sapiens