Pub. Date : 1992 Apr
PMID : 1319933
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Morphogenesis and differentiation of Dictyostelium cells interacting with immobilized glucosides: dependence on DIF production. | Glucosides | tumor necrosis factor | Homo sapiens |
| 2 | In the presence of cyclic AMP, amoebae submerged at high cell density accumulate DIF and differentiate into stalk cells. | Cyclic AMP | tumor necrosis factor | Homo sapiens |
| 3 | Since the responsiveness of cells to DIF-1 is not altered, it appears likely that the effect of the glucoside gel is to block DIF-1 production. | Glucosides | tumor necrosis factor | Homo sapiens |
| 4 | Further, the addition of DIF-1 or DIF-2 stimulates the formation of tight aggregates by cells developing on glucoside gels in the absence of cyclic AMP, thus preventing the rounds of aggregation and disaggregation otherwise seen. | Glucosides | tumor necrosis factor | Homo sapiens |
| 5 | Further, the addition of DIF-1 or DIF-2 stimulates the formation of tight aggregates by cells developing on glucoside gels in the absence of cyclic AMP, thus preventing the rounds of aggregation and disaggregation otherwise seen. | Cyclic AMP | tumor necrosis factor | Homo sapiens |
| 6 | We propose a model in which immobilized glucosides activate a specific receptor ("food sensor") which drives the amoebae toward the vegetative state and inhibits DIF accumulation. | Glucosides | tumor necrosis factor | Homo sapiens |