Pub. Date : 1992 Mar
PMID : 1311994
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The effect of endogenously generated reactive oxygen metabolites on the interaction of human blood monocytes with tumour necrosis factor-alpha (TNF-alpha) was investigated. | Oxygen | tumor necrosis factor | Homo sapiens |
| 2 | ), or to desferrioxamine (DFX), an iron chelator preventing the synthesis of OH., enhanced the specific binding of 125I-TNF-alpha to its receptors. | Deferoxamine | tumor necrosis factor | Homo sapiens |
| 3 | ), or to desferrioxamine (DFX), an iron chelator preventing the synthesis of OH., enhanced the specific binding of 125I-TNF-alpha to its receptors. | Deferoxamine | tumor necrosis factor | Homo sapiens |
| 4 | ), or to desferrioxamine (DFX), an iron chelator preventing the synthesis of OH., enhanced the specific binding of 125I-TNF-alpha to its receptors. | Iron | tumor necrosis factor | Homo sapiens |
| 5 | DFX-induced up-regulation of 125I-TNF-alpha binding depended on the concentration of the drug (1-5 mM) and on the duration of the treatment (1-18 h). | Deferoxamine | tumor necrosis factor | Homo sapiens |
| 6 | Scatchard analysis of binding data revealed that DFX caused an approximately two-fold increase in the number of type II TNF-alpha receptors, with no change in their affinity. | Deferoxamine | tumor necrosis factor | Homo sapiens |