Title : Prothrombin complex concentrates: potentially thrombogenic materials and clues to the mechanism of thrombosis in vivo.

Pub. Date : 1977 Feb

PMID : 12845






2 Functional Relationships(s)
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1 However, after incubation with calcium or various polyamines, large amounts of additional coagulant material, including thrombin, appeared. Calcium coagulation factor II, thrombin Homo sapiens
2 Heparin and antithrombin III not only neutralized the thrombogenic materials present in the thrombogenic concentrate, but also inhibited the de novo generation of coagulant enzymes during incubation with calcium. Calcium serpin family C member 1 Homo sapiens