Title : A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine.

Pub. Date : 2003 Jun

PMID : 12811366






6 Functional Relationships(s)
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1 A pharmacogenetic study of uridine diphosphate-glucuronosyltransferase 2B7 in patients receiving morphine. Morphine UDP glucuronosyltransferase family 2 member B7 Homo sapiens
2 We investigated the variation in the uridine diphosphate-glucuronosyltransferase 2B7 (UGT2B7) gene in patients receiving patient-controlled analgesia with morphine. Morphine UDP glucuronosyltransferase family 2 member B7 Homo sapiens
3 We investigated the variation in the uridine diphosphate-glucuronosyltransferase 2B7 (UGT2B7) gene in patients receiving patient-controlled analgesia with morphine. Morphine UDP glucuronosyltransferase family 2 member B7 Homo sapiens
4 UGT2B7 was sequenced in phenotypic extremes (n = 12) of the distribution of morphine-6-glucuronide/morphine plasma ratios. morphine-6-glucuronide UDP glucuronosyltransferase family 2 member B7 Homo sapiens
5 UGT2B7 was sequenced in phenotypic extremes (n = 12) of the distribution of morphine-6-glucuronide/morphine plasma ratios. Morphine UDP glucuronosyltransferase family 2 member B7 Homo sapiens
6 Interindividual differences in morphine glucuronidation may be the result of genetic variation in UGT2B7, and further studies are indicated. Morphine UDP glucuronosyltransferase family 2 member B7 Homo sapiens