Title : Reduced inhibition and sensitivity to neurosteroids in hippocampus of mice lacking the GABA(A) receptor delta subunit.

Pub. Date : 2003 Aug

PMID : 12702713






1 Functional Relationships(s)
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1 In competition binding experiments, alphaxalone (0.03-1 microM) modulation of [35S]t-butylbicyclophosphorothionate binding was reduced in delta-mutant brain homogenates, indicating that the decreased alphaxalone effects on mIPSCs were due to changes in the GABA(A)R protein. alphaxalone gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 Mus musculus