Title : Glucuronidation of etoposide in human liver microsomes is specifically catalyzed by UDP-glucuronosyltransferase 1A1.

Pub. Date : 2003 May

PMID : 12695347






1 Functional Relationships(s)
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Protein Name
Organism
1 The inhibitory effects of 4-nitrophenol (IC(50) = 121.0 microM) as a typical substrate for UGT1A6 and UGT1A9, imipramine (IC(50) = 393.8 microM) as a typical substrate for UGT1A3 and UGT1A4, and morphine (IC(50) = 109.3 microM) as a typical substrate for UGT2B7 were relatively weak. 4-nitrophenol UDP glucuronosyltransferase family 2 member B7 Homo sapiens