Title : Formation and composition of the C3 activating enzyme complex of the properdin system. Sequential assembly of its components on solid-phase trypsin-agarose.

Pub. Date : 1975 Jul

PMID : 126576






6 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 C3 was activated and the resulting C3b fragment fixed on agarose by incubating C3 with trypsin covalently bound to the agarose. Sepharose complement C3 Homo sapiens
2 C3 was activated and the resulting C3b fragment fixed on agarose by incubating C3 with trypsin covalently bound to the agarose. Sepharose complement C3 Homo sapiens
3 The agarose-C3b intermediate was capable of binding GBG provided Mg++ was present. Sepharose complement C3 Homo sapiens
4 The agarose-C3b intermediate was capable of binding GBG provided Mg++ was present. Magnesium complement C3 Homo sapiens
5 C3b and CVF act in the same way, they form a reversible, weakly active C3 cleaving complex with GBG and Mg++, the activity of which is markedly enhanced but becomes subject to decay when GBG is cleaved by trypsin-like enzymes while bound to CVF or C3b. Magnesium complement C3 Homo sapiens
6 C3b and CVF act in the same way, they form a reversible, weakly active C3 cleaving complex with GBG and Mg++, the activity of which is markedly enhanced but becomes subject to decay when GBG is cleaved by trypsin-like enzymes while bound to CVF or C3b. Magnesium complement C3 Homo sapiens