Title : Identification and localization of a neprilysin-like activity that degrades tachykinin-related peptides in the brain of the cockroach, Leucophaea maderae, and locust, Locusta migratoria.

Pub. Date : 2003 Feb 24

PMID : 12541324






1 Functional Relationships(s)
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Protein Name
Organism
1 The enzyme was acted upon by the NEP inhibitors phosphoramidon (IC(50), 0.64 microM) and thiorphan (IC(50), 1.23 microM), and the detergent-solubilized enzyme had an Mr of approximately 300,000 and a neutral pH optimum. phosphoramidon membrane metalloendopeptidase Homo sapiens