Title : Advanced glycation end product precursors impair epidermal growth factor receptor signaling.

Pub. Date : 2002 May

PMID : 11978653






4 Functional Relationships(s)
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1 AGE precursors induced the formation of EGFR cross-links, as shown by the cross-reactivity of modified EGFR with an anti-N(epsilon)(carboxymethyl)lysine antibody, suggesting that altered EGFR signaling was related to carbonyl-amine reactions on EGFR. N(6)-carboxymethyllysine epidermal growth factor receptor Homo sapiens
2 AGE precursors induced the formation of EGFR cross-links, as shown by the cross-reactivity of modified EGFR with an anti-N(epsilon)(carboxymethyl)lysine antibody, suggesting that altered EGFR signaling was related to carbonyl-amine reactions on EGFR. N(6)-carboxymethyllysine epidermal growth factor receptor Homo sapiens
3 AGE precursors induced the formation of EGFR cross-links, as shown by the cross-reactivity of modified EGFR with an anti-N(epsilon)(carboxymethyl)lysine antibody, suggesting that altered EGFR signaling was related to carbonyl-amine reactions on EGFR. N(6)-carboxymethyllysine epidermal growth factor receptor Homo sapiens
4 AGE precursors induced the formation of EGFR cross-links, as shown by the cross-reactivity of modified EGFR with an anti-N(epsilon)(carboxymethyl)lysine antibody, suggesting that altered EGFR signaling was related to carbonyl-amine reactions on EGFR. N(6)-carboxymethyllysine epidermal growth factor receptor Homo sapiens