Pub. Date : 1975 Dec 19
PMID : 1192181
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A time course for the development of ACh supersensitivity was found to be similar to the time course of AChE loss previosly reported. | Acetylcholine | acetylcholinesterase | Rattus norvegicus |
| 2 | Experiments using physostigmine, an AChE inhibitor, demonstrated that inhibition of AChE can potentiate the effects of ACh in unlesioned preparations, but not in lesioned preparations. | Physostigmine | acetylcholinesterase | Rattus norvegicus |
| 3 | Experiments using physostigmine, an AChE inhibitor, demonstrated that inhibition of AChE can potentiate the effects of ACh in unlesioned preparations, but not in lesioned preparations. | Physostigmine | acetylcholinesterase | Rattus norvegicus |
| 4 | Experiments using physostigmine, an AChE inhibitor, demonstrated that inhibition of AChE can potentiate the effects of ACh in unlesioned preparations, but not in lesioned preparations. | Acetylcholine | acetylcholinesterase | Rattus norvegicus |
| 5 | We conclude: (1) denervation supersensitivity to ACh occurs in the septo-hippocampal pathway; and (2) the supersensitivity is probably due to decreased inactivation of ACh by AChE. | Acetylcholine | acetylcholinesterase | Rattus norvegicus |