Title : The beta-lactam antibiotics, penicillin-G and cefoselis have different mechanisms and sites of action at GABA(A) receptors.

Pub. Date : 2002 Jan

PMID : 11815378






5 Functional Relationships(s)
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1 The beta-lactam antibiotics, penicillin-G and cefoselis have different mechanisms and sites of action at GABA(A) receptors. beta-Lactams gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 Mus musculus
2 These electrophysiological data indicate that PCG and CFSL inhibit GABA(A)-R in a different manner, with PCG acting non-competitively and CFSL competitively. Penicillin G gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 Mus musculus
3 These electrophysiological data indicate that PCG and CFSL inhibit GABA(A)-R in a different manner, with PCG acting non-competitively and CFSL competitively. Penicillin G gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 Mus musculus
4 The mutational study indicates that PCG might act on an identical or nearby site to that of picrotoxin in the channel pore of the GABA(A)-R. Penicillin G gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 Mus musculus
5 The mutational study indicates that PCG might act on an identical or nearby site to that of picrotoxin in the channel pore of the GABA(A)-R. Picrotoxin gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 Mus musculus