Pub. Date : 2000 Sep
PMID : 11003197
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | We analyzed genetic correlations between allelic variation in Gabrg2 and alcohol phenotypes previously measured in the BXD strain means. | Alcohols | gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 | Mus musculus |
2 | RESULTS: Allelic variation in Gabrg2 is correlated genetically with predisposition to acute alcohol withdrawal and may underlie the Alcw3 locus. | Alcohols | gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 | Mus musculus |
3 | In addition, Gabrg2 is associated with ethanol-conditioned taste aversion, ethanol-induced motor incoordination, and ethanol-induced hypothermia. | Ethanol | gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 | Mus musculus |
4 | In addition, Gabrg2 is associated with ethanol-conditioned taste aversion, ethanol-induced motor incoordination, and ethanol-induced hypothermia. | Ethanol | gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 | Mus musculus |
5 | In addition, Gabrg2 is associated with ethanol-conditioned taste aversion, ethanol-induced motor incoordination, and ethanol-induced hypothermia. | Ethanol | gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 | Mus musculus |
6 | CONCLUSIONS: Functionally relevant variation in Gabrg2, or a closely linked gene, is correlated genetically with some, but not all, behavioral responses to alcohol. | Alcohols | gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 | Mus musculus |
7 | The alcohol-related phenotypes associated with Gabrg2 generally may be characterized as debilitating or motivationally negative. | Alcohols | gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2 | Mus musculus |