Pub. Date : 2001 Feb 16
PMID : 10995741
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In the male, these steroids are primarily metabolized into two oxidized (16alpha-hydroxyl and 6beta-hydroxyl) products mainly by the respective, male-specific cytochrome P450 subforms, CYP2C11 and CYP3A2, while they are primarily metabolized into the 5alpha-reduced products by female-predominant 5alpha-reductase in the female. | Steroids | cytochrome P450, family 3, subfamily a, polypeptide 2 | Rattus norvegicus |
2 | In the male, these steroids are primarily metabolized into two oxidized (16alpha-hydroxyl and 6beta-hydroxyl) products mainly by the respective, male-specific cytochrome P450 subforms, CYP2C11 and CYP3A2, while they are primarily metabolized into the 5alpha-reduced products by female-predominant 5alpha-reductase in the female. | 16alpha-hydroxyl | cytochrome P450, family 3, subfamily a, polypeptide 2 | Rattus norvegicus |
3 | In the male, these steroids are primarily metabolized into two oxidized (16alpha-hydroxyl and 6beta-hydroxyl) products mainly by the respective, male-specific cytochrome P450 subforms, CYP2C11 and CYP3A2, while they are primarily metabolized into the 5alpha-reduced products by female-predominant 5alpha-reductase in the female. | 6beta-hydroxyl | cytochrome P450, family 3, subfamily a, polypeptide 2 | Rattus norvegicus |