Title : Advanced glycation end products-cytokine-nitric oxide sequence pathway in the development of diabetic nephropathy: aminoguanidine ameliorates the overexpression of tumour necrosis factor-alpha and inducible nitric oxide synthase in diabetic rat glomeruli.

Pub. Date : 1999 Jul

PMID : 10440132






2 Functional Relationships(s)
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Protein Name
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1 CONCLUSION/INTERPRETATION: This study showed that carboxymethyllysine possibly enhances the expression of inducible nitric oxide synthase by stimulating the expression of TNF-alpha in diabetic rat glomeruli. N(6)-carboxymethyllysine nitric oxide synthase 2 Rattus norvegicus
2 CONCLUSION/INTERPRETATION: This study showed that carboxymethyllysine possibly enhances the expression of inducible nitric oxide synthase by stimulating the expression of TNF-alpha in diabetic rat glomeruli. N(6)-carboxymethyllysine tumor necrosis factor Rattus norvegicus