Pub. Date : 1999 Jul 1
PMID : 10395539
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | BACKGROUND: At M phase, cyclin B1 is phosphorylated in the cytoplasmic retention sequence (CRS), which is required for nuclear export. | 3-cresol | cyclin B1 | Homo sapiens |
| 2 | We show that cyclin B1 rapidly translocates into the nucleus approximately 10 minutes before breakdown of the nuclear envelope, and that this movement requires the CRS phosphorylation sites. | 3-cresol | cyclin B1 | Homo sapiens |
| 3 | Phosphorylation of the CRS creates a nuclear import signal that enhances cyclin B1 import in vitro and in vivo, in a manner distinct from the previously described import of cyclin B1 mediated by importin beta. | 3-cresol | cyclin B1 | Homo sapiens |