Title : The mechanism of activation of NADPH oxidase in the cell-free system: the activation process is primarily catalytic and not through the formation of a stoichiometric complex.

Pub. Date : 1999 Jul 15

PMID : 10393079






1 Functional Relationships(s)
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1 It is commonly assumed that activation of the superoxide-generating NADPH oxidase requires the formation of a stable complex between flavocytochrome b-245 (the gp91phox/p22phox heterodimer) and the cytosolic cofactors p47phox, p67phox and Rac2. Superoxides cytochrome b-245 alpha chain Homo sapiens