Pub. Date : 1999 Jul
PMID : 10391222
12 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The gene mutated in thiamine-responsive anaemia with diabetes and deafness (TRMA) encodes a functional thiamine transporter. | Thiamine | solute carrier family 19 member 2 | Homo sapiens |
| 2 | The gene mutated in thiamine-responsive anaemia with diabetes and deafness (TRMA) encodes a functional thiamine transporter. | Thiamine | solute carrier family 19 member 2 | Homo sapiens |
| 3 | Thiamine-responsive megaloblastic anaemia with diabetes and deafness (TRMA; MIM 249270) is an autosomal recessive disease thought to be due to a defect in thiamine (vitamin B1) transport. | Thiamine | solute carrier family 19 member 2 | Homo sapiens |
| 4 | Thiamine-responsive megaloblastic anaemia with diabetes and deafness (TRMA; MIM 249270) is an autosomal recessive disease thought to be due to a defect in thiamine (vitamin B1) transport. | Thiamine | solute carrier family 19 member 2 | Homo sapiens |
| 5 | Thiamine-responsive megaloblastic anaemia with diabetes and deafness (TRMA; MIM 249270) is an autosomal recessive disease thought to be due to a defect in thiamine (vitamin B1) transport. | Thiamine | solute carrier family 19 member 2 | Homo sapiens |
| 6 | We have previously demonstrated that fibroblasts from people with TRMA lack high-affinity thiamine transport. | Thiamine | solute carrier family 19 member 2 | Homo sapiens |
| 7 | Expression of a gene encoding a known yeast thiamine transporter, THI10 (refs 8-10), in TRMA mutant cells prevents apoptotic cell death in thiamine-depleted medium. | Thiamine | solute carrier family 19 member 2 | Homo sapiens |
| 8 | Expression of a gene encoding a known yeast thiamine transporter, THI10 (refs 8-10), in TRMA mutant cells prevents apoptotic cell death in thiamine-depleted medium. | Thiamine | solute carrier family 19 member 2 | Homo sapiens |
| 9 | On the basis of these studies, we hypothesized that a defective thiamine transporter causes TRMA. | Thiamine | solute carrier family 19 member 2 | Homo sapiens |
| 10 | Here we present evidence that the gene SLC19A2 (for solute carrier family 19 (thiamine transporter), member 2) encodes the first known mammalian thiamine transporter, which we designate thiamine transporter-1 (THTR-1). | Thiamine | solute carrier family 19 member 2 | Homo sapiens |
| 11 | Here we present evidence that the gene SLC19A2 (for solute carrier family 19 (thiamine transporter), member 2) encodes the first known mammalian thiamine transporter, which we designate thiamine transporter-1 (THTR-1). | Thiamine | solute carrier family 19 member 2 | Homo sapiens |
| 12 | Here we present evidence that the gene SLC19A2 (for solute carrier family 19 (thiamine transporter), member 2) encodes the first known mammalian thiamine transporter, which we designate thiamine transporter-1 (THTR-1). | Thiamine | solute carrier family 19 member 2 | Homo sapiens |