Pub. Date : 1999 Apr 15
PMID : 10202034
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Freshly isolated monocytes treated with the protein phosphatase inhibitor okadaic acid secreted high levels of IL-6 protein, which coincided with enhanced binding activity of NF-kappa B as well as with phosphorylation and activation of the ERK1/2 and JNK proteins. | Okadaic Acid | mitogen-activated protein kinase 8 | Homo sapiens |
| 2 | We conclude that okadaic acid-induced IL-6 gene expression is at least partly mediated through the ERK1/2 and JNK pathway-dependent activation of NF-kappa B transcriptional capacity. | Okadaic Acid | mitogen-activated protein kinase 8 | Homo sapiens |