Pub. Date : 1999 Apr
PMID : 10082513
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In addition, Ser18 phosphorylation and transcriptional activation by mouse p53 were diminished in PKR-/- cells after DNA damage induced by the anticancer drug adriamycin or gamma radiation but not by UV radiation. | Doxorubicin | transformation related protein 53, pseudogene | Mus musculus |
| 2 | Furthermore, the specific phosphatidylinositol-3 (PI-3) kinase inhibitor LY294002 inhibited the induction of phosphorylation of Ser18 of p53 by adriamycin to a higher degree in PKR+/+ cells than in PKR-/- cells. | 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one | transformation related protein 53, pseudogene | Mus musculus |
| 3 | Furthermore, the specific phosphatidylinositol-3 (PI-3) kinase inhibitor LY294002 inhibited the induction of phosphorylation of Ser18 of p53 by adriamycin to a higher degree in PKR+/+ cells than in PKR-/- cells. | Doxorubicin | transformation related protein 53, pseudogene | Mus musculus |