Title : Metabolism of risperidone to 9-hydroxyrisperidone by human cytochromes P450 2D6 and 3A4.

Pub. Date : 1999 Feb

PMID : 10048600






2 Functional Relationships(s)
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1 The formation of 9-hydroxyrisperidone is highly correlated with testosterone 6beta-hydroxylase activities, suggesting that inducible CYP3A contributes significantly to the metabolism of risperidone in rat. Paliperidone Palmitate cytochrome P450, family 3, subfamily a, polypeptide 2 Rattus norvegicus
2 The formation of 9-hydroxyrisperidone is highly correlated with testosterone 6beta-hydroxylase activities, suggesting that inducible CYP3A contributes significantly to the metabolism of risperidone in rat. Risperidone cytochrome P450, family 3, subfamily a, polypeptide 2 Rattus norvegicus