Title : Ligand-activated retinoic acid receptor inhibits AP-1 transactivation by disrupting c-Jun/c-Fos dimerization.

Pub. Date : 1999 Feb

PMID : 9973257






1 Functional Relationships(s)
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1 Using a mammalian two-hybrid system, we report here that human RARalpha (hRARalpha) can disrupt in a RA-dependent manner the homo- and heterodimerization properties of c-Jun and c-Fos. Tretinoin Fos proto-oncogene, AP-1 transcription factor subunit Homo sapiens