Pub. Date : 1999 Feb
PMID : 9973257
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Using a mammalian two-hybrid system, we report here that human RARalpha (hRARalpha) can disrupt in a RA-dependent manner the homo- and heterodimerization properties of c-Jun and c-Fos. | Tretinoin | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |
| 2 | This inhibition of dimerization is cell specific, occurring only in those cells that exhibit RA-induced repression of AP-1 transcriptional activity. | Tretinoin | Jun proto-oncogene, AP-1 transcription factor subunit | Homo sapiens |