Pub. Date : 1999 Feb
PMID : 9950898
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effect of azelastine on platelet-activating factor-induced microvascular leakage in rat airways. | azelastine | PCNA clamp associated factor | Rattus norvegicus |
| 2 | Pretreatment with azelastine inhibited PAF-induced vascular leakage without affecting neutrophil accumulation. | azelastine | PCNA clamp associated factor | Rattus norvegicus |
| 3 | PAF increased neutrophil elastase contents in bronchoalveolar lavage fluid, an effect that was inhibited by azelastine. | azelastine | PCNA clamp associated factor | Rattus norvegicus |
| 4 | Therefore, azelastine attenuates PAF-induced airway mucosal microvascular leakage, probably involving inhibition of the release of neutrophil elastase from activated neutrophils. | azelastine | PCNA clamp associated factor | Rattus norvegicus |