Title : Nonstressed rat model of acute endotoxemia that unmasks the endotoxin-induced TNF-alpha response.

Pub. Date : 1999 Feb

PMID : 9950870






2 Functional Relationships(s)
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1 Previous investigators have demonstrated that the tumor necrosis factor-alpha (TNF-alpha) response to endotoxin is inhibited by exogenous corticosterone or catecholamines both in vitro and in vivo, whereas others have reported that surgical and nonsurgical stress increase the endogenous concentrations of these stress-induced hormones. Catecholamines tumor necrosis factor Rattus norvegicus
2 Previous investigators have demonstrated that the tumor necrosis factor-alpha (TNF-alpha) response to endotoxin is inhibited by exogenous corticosterone or catecholamines both in vitro and in vivo, whereas others have reported that surgical and nonsurgical stress increase the endogenous concentrations of these stress-induced hormones. Catecholamines tumor necrosis factor Rattus norvegicus