Title : Phenobarbital promotes liver growth in c-myc/TGF-alpha transgenic mice by inducing hypertrophy and inhibiting apoptosis.

Pub. Date : 1999 Jan

PMID : 9934848






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Throughout the study, PB-treated animals showed markedly lower levels of TGF-beta1 ligand, coincident with an elevated level of the anti-apoptotic protein Bcl-2. Phenobarbital transforming growth factor, beta 1 Mus musculus
2 We conclude from our data that PB stimulates liver growth in double transgenic c-myc/TGF-alpha mice by induction of liver hypertrophy and inhibition of apoptosis, brought about by both a decrease in signaling through the TGF-beta pathway and an increase in Bcl-2. Phenobarbital transforming growth factor, beta 1 Mus musculus