Pub. Date : 1999 Feb 15
PMID : 9927726
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The rad27 deletion mutants are highly sensitive to methylmethane sulfonate (MMS). | Methyl Methanesulfonate | multifunctional nuclease RAD27 | Saccharomyces cerevisiae S288C |
| 2 | The rad27 deletion mutants are highly sensitive to methylmethane sulfonate (MMS). | Methyl Methanesulfonate | multifunctional nuclease RAD27 | Saccharomyces cerevisiae S288C |
| 3 | By examining the role of Rad27 in different modes of DNA excision repair, we wish to understand why the cytotoxic effect of MMS is dramatically enhanced in the absence of Rad27. | Methyl Methanesulfonate | multifunctional nuclease RAD27 | Saccharomyces cerevisiae S288C |
| 4 | Surprisingly, we found that Apn1 endonuclease sensitizes rad27 mutant cells to MMS. | Methyl Methanesulfonate | multifunctional nuclease RAD27 | Saccharomyces cerevisiae S288C |
| 5 | Deleting the APN1 gene largely restored the resistance of rad27 mutants to MMS. | Methyl Methanesulfonate | multifunctional nuclease RAD27 | Saccharomyces cerevisiae S288C |