Title : Effects of pro- and antioxidative compounds on renal production of erythropoietin.

Pub. Date : 1999 Feb

PMID : 9927288






2 Functional Relationships(s)
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1 Under normoxic conditions, the iron chelator desferrioxamine and the antioxidant vitamin A increased renal Epo production, mimicking hypoxic induction. Deferoxamine erythropoietin Homo sapiens
2 The inhibition of Epo formation by reactive O2 species could be completely antagonized by desferrioxamine and the hydroxyl radical-(OH*)-scavenger tetramethylthiourea. Deferoxamine erythropoietin Homo sapiens