Title : Synchronous fluctuations of blood insulin and lactate concentrations in humans.

Pub. Date : 1999 Jan

PMID : 9920088






6 Functional Relationships(s)
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1 Only the close temporal relationship between insulin and lactate release persisted during nighttime. Lactic Acid insulin Homo sapiens
2 The temporal coupling and pattern synchrony between insulin and lactate were correlated inversely with insulin sensitivity, and positively with the degree of abdominal obesity. Lactic Acid insulin Homo sapiens
3 Our results suggest that: 1) the concentration of lactate, an indicator of cellular energy metabolism, fluctuates periodically in vivo; 2) the lactate concentrations fluctuate in synchrony with insulin pulses; and 3) such coupling is more pronounced in obese, insulin-resistant individuals. Lactic Acid insulin Homo sapiens
4 Our results suggest that: 1) the concentration of lactate, an indicator of cellular energy metabolism, fluctuates periodically in vivo; 2) the lactate concentrations fluctuate in synchrony with insulin pulses; and 3) such coupling is more pronounced in obese, insulin-resistant individuals. Lactic Acid insulin Homo sapiens
5 Our results suggest that: 1) the concentration of lactate, an indicator of cellular energy metabolism, fluctuates periodically in vivo; 2) the lactate concentrations fluctuate in synchrony with insulin pulses; and 3) such coupling is more pronounced in obese, insulin-resistant individuals. Lactic Acid insulin Homo sapiens
6 Our results suggest that: 1) the concentration of lactate, an indicator of cellular energy metabolism, fluctuates periodically in vivo; 2) the lactate concentrations fluctuate in synchrony with insulin pulses; and 3) such coupling is more pronounced in obese, insulin-resistant individuals. Lactic Acid insulin Homo sapiens