Title : Determination of the enzymes responsible for activation of the heterocyclic amine 2-amino-3-methylimidazo[4,5-f]quinoline in the human breast.

Pub. Date : 1998 Dec

PMID : 9918136






1 Functional Relationships(s)
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1 In cultured epithelial cells, IQ-DNA adduct formation and CYP1A1, but not CYP1B1 expression were induced threefold by benz[a]anthracene treatment; IQ-DNA adduct formation was inhibited by alpha-naphthoflavone. anthracene cytochrome P450 family 1 subfamily A member 1 Homo sapiens