Title : Specific NF-kappaB blockade selectively inhibits tumour necrosis factor-alpha-induced COX-2 but not constitutive COX-1 gene expression in HT-29 cells.

Pub. Date : 1998 Dec

PMID : 9893042






1 Functional Relationships(s)
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1 Selective inhibition of COX-2 expression with the NF-kappaB super-repressor may be useful in distinguishing the role of inducible versus constitutive prostaglandins in intestinal function and provides greater specificity than pharmacological inhibitors. Prostaglandins nuclear factor kappa B subunit 1 Homo sapiens