Title : Insulin-mediated modulation of cytochrome P450 gene induction profiles in primary rat hepatocyte cultures.

Pub. Date : 1999

PMID : 9890442






1 Functional Relationships(s)
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1 Culturing in the absence of insulin produced 1.5-2-fold increases in the induction magnitude of CYP2B1 and CYP2B2 mRNA expression resulting from PB exposures, without altering the bell-shaped dose-response curve characteristic of this agent. Phenobarbital cytochrome P450, family 2, subfamily b, polypeptide 2 Rattus norvegicus