Pub. Date : 1998 Dec
PMID : 9872368
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | SDS (> or =0.05% w/v) resulted in significant inhibition both of basal and BH4-stimulated activities of NOS III, but the latter responded more sensitively. | sapropterin | nitric oxide synthase 3 | Homo sapiens |
| 2 | Considering that basal activity is due to the presence of endogenous BH4 tightly bound to the enzyme, this differential sensitivity of basal and BH4-stimulated enzyme activities to SDS may be related to a putative differential protective effect of BH4 on the two subunits of the NOS III dimer. | sapropterin | nitric oxide synthase 3 | Homo sapiens |
| 3 | Considering that basal activity is due to the presence of endogenous BH4 tightly bound to the enzyme, this differential sensitivity of basal and BH4-stimulated enzyme activities to SDS may be related to a putative differential protective effect of BH4 on the two subunits of the NOS III dimer. | sapropterin | nitric oxide synthase 3 | Homo sapiens |
| 4 | Considering that basal activity is due to the presence of endogenous BH4 tightly bound to the enzyme, this differential sensitivity of basal and BH4-stimulated enzyme activities to SDS may be related to a putative differential protective effect of BH4 on the two subunits of the NOS III dimer. | sapropterin | nitric oxide synthase 3 | Homo sapiens |
| 5 | A model describing the interaction between BH4 and NOS III, and its implications on the physiology and pathology of the human placenta, is discussed. | sapropterin | nitric oxide synthase 3 | Homo sapiens |