Title : Fluvoxamine is a potent inhibitor of the metabolism of caffeine in vitro.

Pub. Date : 1998 Dec

PMID : 9868741






2 Functional Relationships(s)
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1 The selective serotonin re-uptake inhibitor, fluvoxamine, is a very potent inhibitor of CYP1A2, and accordingly causes pharmacokinetic interactions with drugs metabolised by CYP1A2, such as caffeine, theophylline, imipramine, tacrine and clozapine. Tacrine cytochrome P450 family 1 subfamily A member 2 Homo sapiens
2 The selective serotonin re-uptake inhibitor, fluvoxamine, is a very potent inhibitor of CYP1A2, and accordingly causes pharmacokinetic interactions with drugs metabolised by CYP1A2, such as caffeine, theophylline, imipramine, tacrine and clozapine. Tacrine cytochrome P450 family 1 subfamily A member 2 Homo sapiens