Pub. Date : 1998 Dec
PMID : 9868741
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The CYP3A4 inhibitors, ketoconazole and bromocriptine, inhibited 1,3,7-trimethyluric acid formation with Kis of 0.75 microM and 5 microM, respectively, thus further supporting the involvement of CYP3A4 in the 8-hydroxylation of caffeine. | 1,3,7-trimethyluric acid | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 2 | The CYP3A4 inhibitors, ketoconazole and bromocriptine, inhibited 1,3,7-trimethyluric acid formation with Kis of 0.75 microM and 5 microM, respectively, thus further supporting the involvement of CYP3A4 in the 8-hydroxylation of caffeine. | 1,3,7-trimethyluric acid | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |