Title : Fluvoxamine is a potent inhibitor of the metabolism of caffeine in vitro.

Pub. Date : 1998 Dec

PMID : 9868741






1 Functional Relationships(s)
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1 The formation of 1,7-dimethylxanthine was virtually abolished by 10 microM of fluvoxamine, indicating that the N3-demethylation of caffeine is almost exclusively catalysed by CYP1A2. Theobromine cytochrome P450 family 1 subfamily A member 2 Homo sapiens