Title : Activation of p38 mitogen-activated protein kinase by lipopolysaccharide in human neutrophils requires nitric oxide-dependent cGMP accumulation.

Pub. Date : 1999 Jan 1

PMID : 9867877






1 Functional Relationships(s)
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1 Increasing cellular cGMP with phosphodiesterase inhibitors, by stimulation of soluble guanylyl cyclase with YC-1 or with exogenous dibutyryl cGMP resulted in mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 3,6 (MEK3,6) activation and phosphorylation of p38. Cyclic GMP RNA binding motif single stranded interacting protein 1 Homo sapiens