Title : p38 mitogen-activated protein kinase regulates cyclooxygenase-2 mRNA stability and transcription in lipopolysaccharide-treated human monocytes.

Pub. Date : 1999 Jan 1

PMID : 9867839






1 Functional Relationships(s)
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1 We have previously shown that the pyridinyl imidazole SB 203580, which inhibits it, blocks the interleukin-1 induction of cyclooxygenase-2 (COX-2) and matrix metalloproteinase 1 and 3 mRNAs in fibroblasts. 2-(1H-imidazol-2-yl)pyridine interleukin 1 alpha Homo sapiens