Title : Negative regulation of interleukin-1beta-activated neutral sphingomyelinase by protein kinase C in rat mesangial cells.

Pub. Date : 1998 Nov 27

PMID : 9862447






1 Functional Relationships(s)
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1 Long-term incubation (24 h) of mesangial cells with TPA, which downregulates PKC-alpha, -delta, and -epsilon isoenzymes, resulted in a recovery of IL-1beta-stimulated neutral SMase activity as well as ceramide formation. Tetradecanoylphorbol Acetate interleukin 1 beta Rattus norvegicus