Pub. Date : 1999 Jan
PMID : 9858533
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We have previously reported that PTB binds to a pyrimidine tract within an RNA processing enhancer located adjacent to an alternative 3"-terminal exon within the gene coding for calcitonin and calcitonin gene-related peptide. | pyrimidine | polypyrimidine tract binding protein 1 | Homo sapiens |
| 2 | Here we show that the binding of PTB to the enhancer pyrimidine tract is functional in that exon inclusion increases when in vivo levels of PTB increase. | pyrimidine | polypyrimidine tract binding protein 1 | Homo sapiens |
| 3 | Here we show that the binding of PTB to the enhancer pyrimidine tract is functional in that exon inclusion increases when in vivo levels of PTB increase. | pyrimidine | polypyrimidine tract binding protein 1 | Homo sapiens |
| 4 | The binding of PTB was antagonistic to the binding of U2AF to the enhancer-located pyrimidine tract. | pyrimidine | polypyrimidine tract binding protein 1 | Homo sapiens |
| 5 | These observations suggest a dual role for PTB in facilitating recognition of exon 4: binding to the enhancer pyrimidine tract to interrupt productive recognition of the enhancer pseudoexon by splicing factors and interacting with the poly(A) site to positively affect polyadenylation. | pyrimidine | polypyrimidine tract binding protein 1 | Homo sapiens |