Title : A p38 MAP kinase inhibitor regulates stability of interleukin-1-induced cyclooxygenase-2 mRNA.

Pub. Date : 1998 Nov 13

PMID : 9849881






1 Functional Relationships(s)
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1 SB 203580, an inhibitor of p38 MAPK, in the range 0.1-1 microM inhibited IL-1-stimulated PGE2 (but not arachidonic acid) release and this was associated with inhibition of induction of COX-2 protein and mRNA. SB 203580 mitochondrially encoded cytochrome c oxidase II Homo sapiens