Title : Does the lack of the P-glycoprotein efflux pump in neutrophils explain the efficacy of colchicine in familial Mediterranean fever and other inflammatory diseases?

Pub. Date : 1998 Nov

PMID : 9848464






2 Functional Relationships(s)
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1 Does the lack of the P-glycoprotein efflux pump in neutrophils explain the efficacy of colchicine in familial Mediterranean fever and other inflammatory diseases? Colchicine ATP binding cassette subfamily B member 1 Homo sapiens
2 We propose that the preferential accumulation of colchicine in neutrophils compared with lymphomonocytes is due to the absence of the P-gly efflux pump in the former. Colchicine ATP binding cassette subfamily B member 1 Homo sapiens