Title : The role of alcohol dehydrogenase in the metabolism of the colon carcinogen methylazoxymethanol.

Pub. Date : 1998 Sep

PMID : 9848112






3 Functional Relationships(s)
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1 The role of alcohol dehydrogenase in the metabolism of the colon carcinogen methylazoxymethanol. methylazoxymethanol aldo-keto reductase family 1, member A1 (aldehyde reductase) Mus musculus
2 The aim of this study was to determine whether the cytosolic enzyme alcohol dehydrogenase (ADH) activates methylazoxymethanol (MAM) in the mouse colon and whether differential tumor susceptibility in the mouse is dependent, in part, on strain-related differences in MAM metabolism by ADH. methylazoxymethanol aldo-keto reductase family 1, member A1 (aldehyde reductase) Mus musculus
3 The aim of this study was to determine whether the cytosolic enzyme alcohol dehydrogenase (ADH) activates methylazoxymethanol (MAM) in the mouse colon and whether differential tumor susceptibility in the mouse is dependent, in part, on strain-related differences in MAM metabolism by ADH. methylazoxymethanol aldo-keto reductase family 1, member A1 (aldehyde reductase) Mus musculus