Title : Effects of interleukin-4 on the expression and activity of prostaglandin endoperoxide H synthase-2 in amnion-derived WISH cells.

Pub. Date : 1998 Dec

PMID : 9845672






1 Functional Relationships(s)
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1 We conclude that IL-4 inhibits PGHS-2 mRNA and protein production in cytokine-stimulated WISH cells, but does not affect EGF-stimulated PGE2 production, suggesting that EGF can induce prostaglandin biosynthesis by a mechanism other than through increased PGHS-2 expression. Prostaglandins epidermal growth factor Homo sapiens